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Beta-Secretase 1 Underlies Reactive Astrocytes and Endothelial Disruption in Neurodegeneration
Dysfunction in the neurovascular unit (NVU) is a key component in the progressive deterioration of Alzheimer’s disease (AD) and is critical in vascular dementia. Recent studies have shown that inflammation plays early and perhaps causal roles in the pathogenesis of AD related to NVU damage, possibly...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136516/ https://www.ncbi.nlm.nih.gov/pubmed/34025357 http://dx.doi.org/10.3389/fncel.2021.656832 |