Beta-Secretase 1 Underlies Reactive Astrocytes and Endothelial Disruption in Neurodegeneration

Dysfunction in the neurovascular unit (NVU) is a key component in the progressive deterioration of Alzheimer’s disease (AD) and is critical in vascular dementia. Recent studies have shown that inflammation plays early and perhaps causal roles in the pathogenesis of AD related to NVU damage, possibly...

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Detalles Bibliográficos
Autores principales: Chacón-Quintero, María Victoria, Pineda-López, Lina Gisela, Villegas-Lanau, Carlos Andrés, Posada-Duque, Rafael, Cardona-Gómez, Gloria Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136516/
https://www.ncbi.nlm.nih.gov/pubmed/34025357
http://dx.doi.org/10.3389/fncel.2021.656832

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