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DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist

The efficient spread of SARS-CoV-2 resulted in a unique pandemic in modern history. Despite early identification of ACE2 as the receptor for viral spike protein, much remains to be understood about the molecular events behind viral dissemination. We evaluated the contribution of C-type lectin recept...

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Detalles Bibliográficos
Autores principales: Thépaut, Michel, Luczkowiak, Joanna, Vivès, Corinne, Labiod, Nuria, Bally, Isabelle, Lasala, Fátima, Grimoire, Yasmina, Fenel, Daphna, Sattin, Sara, Thielens, Nicole, Schoehn, Guy, Bernardi, Anna, Delgado, Rafael, Fieschi, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136665/
https://www.ncbi.nlm.nih.gov/pubmed/34015061
http://dx.doi.org/10.1371/journal.ppat.1009576