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Dynamics of SAS-I mediated H4 K16 acetylation during DNA replication in yeast

The acetylation of H4 lysine 16 (H4 K16Ac) in Saccharomyces cerevisiae counteracts the binding of the heterochromatin complex SIR to chromatin and inhibits gene silencing. Contrary to other histone acetylation marks, the H4 K16Ac level is high on genes with low transcription, whereas highly transcri...

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Detalles Bibliográficos
Autores principales: Boltengagen, Mark, Samel-Pommerencke, Anke, Fechtig, David, Ehrenhofer-Murray, Ann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136709/
https://www.ncbi.nlm.nih.gov/pubmed/34014972
http://dx.doi.org/10.1371/journal.pone.0251660