Extracellular DJ-1 induces sterile inflammation in the ischemic brain

Inflammation is implicated in the onset and progression of various diseases, including cerebral pathologies. Here, we report that DJ-1, which plays a role within cells as an antioxidant protein, functions as a damage-associated molecular pattern (DAMP) and triggers inflammation if released from dead...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Koutarou, Sakai, Seiichiro, Tsuyama, Jun, Nakamura, Akari, Otani, Kento, Kurabayashi, Kumiko, Yogiashi, Yoshiko, Masai, Hisao, Shichita, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136727/
https://www.ncbi.nlm.nih.gov/pubmed/34014921
http://dx.doi.org/10.1371/journal.pbio.3000939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136727/
https://www.ncbi.nlm.nih.gov/pubmed/34014921
http://dx.doi.org/10.1371/journal.pbio.3000939

Ejemplares similares