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Molecular subtyping of Alzheimer’s disease with consensus non-negative matrix factorization
Alzheimer’s disease (AD) is a heterogeneous disease and exhibits diverse clinical presentations and disease progression. Some pathological and anatomical subtypes have been proposed. However, these subtypes provide a limited mechanistic understanding for AD. Leveraging gene expression data of 222 AD...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136734/ https://www.ncbi.nlm.nih.gov/pubmed/34014928 http://dx.doi.org/10.1371/journal.pone.0250278 |