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Molecular subtyping of Alzheimer’s disease with consensus non-negative matrix factorization

Alzheimer’s disease (AD) is a heterogeneous disease and exhibits diverse clinical presentations and disease progression. Some pathological and anatomical subtypes have been proposed. However, these subtypes provide a limited mechanistic understanding for AD. Leveraging gene expression data of 222 AD...

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Detalles Bibliográficos
Autores principales: Zheng, Chunlei, Xu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136734/
https://www.ncbi.nlm.nih.gov/pubmed/34014928
http://dx.doi.org/10.1371/journal.pone.0250278