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The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity

Base-modification can occur throughout a transfer RNA molecule; however, elaboration is particularly prevalent at position 34 of the anticodon loop (the wobble position), where it functions to influence protein translation. Previously, we demonstrated that the queuosine modification at position 34 c...

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Detalles Bibliográficos
Autores principales: Fergus, Claire, Al-qasem, Mashael, Cotter, Michelle, McDonnell, Ciara M, Sorrentino, Emiliano, Chevot, Franciane, Hokamp, Karsten, Senge, Mathias O, Southern, John M, Connon, Stephen J, Kelly, Vincent P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136771/
https://www.ncbi.nlm.nih.gov/pubmed/34009357
http://dx.doi.org/10.1093/nar/gkab289