SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes

Spatially resolved gene expression profiles are key to understand tissue organization and function. However, spatial transcriptomics (ST) profiling techniques lack single-cell resolution and require a combination with single-cell RNA sequencing (scRNA-seq) information to deconvolute the spatially in...

Descripción completa

Detalles Bibliográficos
Autores principales: Elosua-Bayes, Marc, Nieto, Paula, Mereu, Elisabetta, Gut, Ivo, Heyn, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136778/
https://www.ncbi.nlm.nih.gov/pubmed/33544846
http://dx.doi.org/10.1093/nar/gkab043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136778/
https://www.ncbi.nlm.nih.gov/pubmed/33544846
http://dx.doi.org/10.1093/nar/gkab043

Ejemplares similares