Molecular structure, DNA binding mode, photophysical properties and recommendations for use of SYBR Gold

SYBR Gold is a commonly used and particularly bright fluorescent DNA stain, however, its chemical structure is unknown and its binding mode to DNA remains controversial. Here, we solve the structure of SYBR Gold by NMR and mass spectrometry to be [2-(4-{[diethyl(methyl)ammonio]methyl}phenyl)-6-metho...

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Detalles Bibliográficos
Autores principales: Kolbeck, Pauline J, Vanderlinden, Willem, Gemmecker, Gerd, Gebhardt, Christian, Lehmann, Martin, Lak, Aidin, Nicolaus, Thomas, Cordes, Thorben, Lipfert, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136779/
https://www.ncbi.nlm.nih.gov/pubmed/33905507
http://dx.doi.org/10.1093/nar/gkab265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136779/
https://www.ncbi.nlm.nih.gov/pubmed/33905507
http://dx.doi.org/10.1093/nar/gkab265

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