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G-Quadruplexes as pathogenic drivers in neurodegenerative disorders

G-quadruplexes (G4s), higher-order DNA and RNA secondary structures featuring guanine-rich nucleic acid sequences with various conformations, are widely distributed in the human genome. These structural motifs are known to participate in basic cellular processes, including transcription, splicing, a...

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Detalles Bibliográficos
Autores principales: Wang, Ernest, Thombre, Ravi, Shah, Yajas, Latanich, Rachel, Wang, Jiou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136783/
https://www.ncbi.nlm.nih.gov/pubmed/33784396
http://dx.doi.org/10.1093/nar/gkab164