Slow chromatin dynamics enhances promoter accessibility to transcriptional condensates

Enhancers are DNA sequences at a long genomic distance from target genes. Recent experiments suggest that enhancers are anchored to the surfaces of condensates of transcription machinery and that the loop extrusion process enhances the transcription level of their target genes. Here, we theoreticall...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamoto, Tetsuya, Sakaue, Takahiro, Schiessel, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136786/
https://www.ncbi.nlm.nih.gov/pubmed/33885786
http://dx.doi.org/10.1093/nar/gkab275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136786/
https://www.ncbi.nlm.nih.gov/pubmed/33885786
http://dx.doi.org/10.1093/nar/gkab275

Ejemplares similares