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Repriming DNA synthesis: an intrinsic restart pathway that maintains efficient genome replication
To bypass a diverse range of fork stalling impediments encountered during genome replication, cells possess a variety of DNA damage tolerance (DDT) mechanisms including translesion synthesis, template switching, and fork reversal. These pathways function to bypass obstacles and allow efficient DNA s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136793/ https://www.ncbi.nlm.nih.gov/pubmed/33744934 http://dx.doi.org/10.1093/nar/gkab176 |