Repriming DNA synthesis: an intrinsic restart pathway that maintains efficient genome replication

To bypass a diverse range of fork stalling impediments encountered during genome replication, cells possess a variety of DNA damage tolerance (DDT) mechanisms including translesion synthesis, template switching, and fork reversal. These pathways function to bypass obstacles and allow efficient DNA s...

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Detalles Bibliográficos
Autores principales: Bainbridge, Lewis J, Teague, Rebecca, Doherty, Aidan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136793/
https://www.ncbi.nlm.nih.gov/pubmed/33744934
http://dx.doi.org/10.1093/nar/gkab176

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