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Estimation of peptide elongation times from ribosome profiling spectra

Ribosome profiling spectra bear rich information on translation control and dynamics. Yet, due to technical biases in library generation, extracting quantitative measures of discrete translation events has remained elusive. Using maximum likelihood statistics and data set from Escherichia coli we de...

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Detalles Bibliográficos
Autores principales: Pavlov, Michael Y, Ullman, Gustaf, Ignatova, Zoya, Ehrenberg, Måns
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136808/
https://www.ncbi.nlm.nih.gov/pubmed/33885812
http://dx.doi.org/10.1093/nar/gkab260