PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases

The CCCH-type zinc finger (ZnF) containing ZC3H12 ribonucleases are crucial in post-transcriptional immune homoeostasis with ZC3H12A being the only structurally studied member of the family. In this study, we present a structural-biochemical characterization of ZC3H12C, which is linked with chronic...

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Detalles Bibliográficos
Autores principales: Garg, Ankur, Roske, Yvette, Yamada, Shinnosuke, Uehata, Takuya, Takeuchi, Osamu, Heinemann, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136824/
https://www.ncbi.nlm.nih.gov/pubmed/33950203
http://dx.doi.org/10.1093/nar/gkab316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136824/
https://www.ncbi.nlm.nih.gov/pubmed/33950203
http://dx.doi.org/10.1093/nar/gkab316

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