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PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases
The CCCH-type zinc finger (ZnF) containing ZC3H12 ribonucleases are crucial in post-transcriptional immune homoeostasis with ZC3H12A being the only structurally studied member of the family. In this study, we present a structural-biochemical characterization of ZC3H12C, which is linked with chronic...
Autores principales: | Garg, Ankur, Roske, Yvette, Yamada, Shinnosuke, Uehata, Takuya, Takeuchi, Osamu, Heinemann, Udo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136824/ https://www.ncbi.nlm.nih.gov/pubmed/33950203 http://dx.doi.org/10.1093/nar/gkab316 |
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