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FreeHi-C simulates high fidelity Hi-C data for benchmarking and data augmentation
Ability to simulate high-throughput chromatin conformation (Hi-C) data is foundational for benchmarking Hi-C data analysis methods. Here we present a non-parametric strategy named FreeHi-C to simulate Hi-C data from the interacting genome fragments. Data from FreeHi-C exhibit high fidelity to biolog...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136837/ https://www.ncbi.nlm.nih.gov/pubmed/31712779 http://dx.doi.org/10.1038/s41592-019-0624-3 |