Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever

Importing necessary metabolites into the mitochondrial matrix is a crucial step of fuel choice during stress adaptation. Branched chain-amino acids (BCAAs) are essential amino acids needed for anabolic processes, but they are also imported into the mitochondria for catabolic reactions. What controls...

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Detalles Bibliográficos
Autores principales: Yoneshiro, Takeshi, Kataoka, Naoya, Walejko, Jacquelyn M, Ikeda, Kenji, Brown, Zachary, Yoneshiro, Momoko, Crown, Scott B, Osawa, Tsuyoshi, Sakai, Juro, McGarrah, Robert W, White, Phillip J, Nakamura, Kazuhiro, Kajimura, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137140/
https://www.ncbi.nlm.nih.gov/pubmed/33944778
http://dx.doi.org/10.7554/eLife.66865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137140/
https://www.ncbi.nlm.nih.gov/pubmed/33944778
http://dx.doi.org/10.7554/eLife.66865

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