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Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics

Innate immune cellular effectors are actively consumed during systemic inflammation, but the systemic traffic and the mechanisms that support their replenishment remain unknown. Here, we demonstrate that acute systemic inflammation induces the emergent activation of a previously unrecognized system...

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Detalles Bibliográficos
Autores principales: Serrano-Lopez, Juana, Hegde, Shailaja, Kumar, Sachin, Serrano, Josefina, Fang, Jing, Wellendorf, Ashley M, Roche, Paul A, Rangel, Yamileth, Carrington, Leolene J, Geiger, Hartmut, Grimes, H Leighton, Luther, Sanjiv, Maillard, Ivan, Sanchez-Garcia, Joaquin, Starczynowski, Daniel T, Cancelas, Jose A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137144/
https://www.ncbi.nlm.nih.gov/pubmed/33830019
http://dx.doi.org/10.7554/eLife.66190