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Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics
Innate immune cellular effectors are actively consumed during systemic inflammation, but the systemic traffic and the mechanisms that support their replenishment remain unknown. Here, we demonstrate that acute systemic inflammation induces the emergent activation of a previously unrecognized system...
Autores principales: | Serrano-Lopez, Juana, Hegde, Shailaja, Kumar, Sachin, Serrano, Josefina, Fang, Jing, Wellendorf, Ashley M, Roche, Paul A, Rangel, Yamileth, Carrington, Leolene J, Geiger, Hartmut, Grimes, H Leighton, Luther, Sanjiv, Maillard, Ivan, Sanchez-Garcia, Joaquin, Starczynowski, Daniel T, Cancelas, Jose A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137144/ https://www.ncbi.nlm.nih.gov/pubmed/33830019 http://dx.doi.org/10.7554/eLife.66190 |
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