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ZC3H4 restricts non-coding transcription in human cells

The human genome encodes thousands of non-coding RNAs. Many of these terminate early and are then rapidly degraded, but how their transcription is restricted is poorly understood. In a screen for protein-coding gene transcriptional termination factors, we identified ZC3H4. Its depletion causes upreg...

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Detalles Bibliográficos
Autores principales: Estell, Chris, Davidson, Lee, Steketee, Pieter C, Monier, Adam, West, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137146/
https://www.ncbi.nlm.nih.gov/pubmed/33913806
http://dx.doi.org/10.7554/eLife.67305