Anti-pituitary antibodies and susceptible human leukocyte antigen alleles as predictive biomarkers for pituitary dysfunction induced by immune checkpoint inhibitors

BACKGROUND: Pituitary dysfunction is a life-threatening immune-related adverse event (irAE) induced by immune checkpoint inhibitors (ICIs). To date, it is not possible to identify patients who may develop pituitary irAEs prior to ICI treatment. The aim of this study was to characterize the predispos...

Descripción completa

Detalles Bibliográficos
Autores principales: Kobayashi, Tomoko, Iwama, Shintaro, Sugiyama, Daisuke, Yasuda, Yoshinori, Okuji, Takayuki, Ito, Masaaki, Ito, Sachiko, Sugiyama, Mariko, Onoue, Takeshi, Takagi, Hiroshi, Hagiwara, Daisuke, Ito, Yoshihiro, Suga, Hidetaka, Banno, Ryoichi, Nishikawa, Hiroyoshi, Arima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137231/
https://www.ncbi.nlm.nih.gov/pubmed/34011534
http://dx.doi.org/10.1136/jitc-2021-002493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137231/
https://www.ncbi.nlm.nih.gov/pubmed/34011534
http://dx.doi.org/10.1136/jitc-2021-002493

Ejemplares similares