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The relationship between miRNA-26b and connective tissue growth factor in rat models of aortic banding and debanding

BACKGROUND/AIMS: Connective tissue growth factor (CTGF) is a profibrotic factor implicated in pressure overload-mediated myocardial fibrosis. In this study, we determined the role of predicted CTGF-targeting microRNAs (miRNAs) in rat models of aortic stenosis and reverse cardiac remodeling. METHODS:...

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Detalles Bibliográficos
Autores principales: Cho, Jung Sun, Lee, Jongho, Park, Ki Cheol, Yang, Keum-Jin, Cho, Eun Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137408/
https://www.ncbi.nlm.nih.gov/pubmed/31875666
http://dx.doi.org/10.3904/kjim.2019.120