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MicroRNA-21 inhibition attenuates airway inflammation and remodelling by modulating the transforming growth factor β–Smad7 pathway

BACKGROUND/AIMS: Current asthma therapies remain unsatisfactory for controlling airway remodelling in asthma. MicroRNA-21 is a key player in asthma pathogenesis, but the molecular mechanisms underlying its effects on airway remodelling are not completely understood. We investigated the effects of in...

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Detalles Bibliográficos
Autores principales: Hur, Jung, Rhee, Chin Kook, Lee, Sook Young, Kim, Young Kyoon, Kang, Ji Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137415/
https://www.ncbi.nlm.nih.gov/pubmed/33601867
http://dx.doi.org/10.3904/kjim.2020.132