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Mdivi-1 induces spindle abnormalities and augments taxol cytotoxicity in MDA-MB-231 cells

Taxol is a first-line chemotherapeutic for numerous cancers, including the highly refractory triple-negative breast cancer (TNBC). However, it is often associated with toxic side effects and chemoresistance in breast cancer patients, which greatly limits the clinical utility of the drug. Hence, comp...

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Detalles Bibliográficos
Autores principales: Fang, Chieh-Ting, Kuo, Hsiao-Hui, Yuan, Chia-Jung, Yao, Jhong-Syuan, Yih, Ling-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137698/
https://www.ncbi.nlm.nih.gov/pubmed/34016960
http://dx.doi.org/10.1038/s41420-021-00495-z