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Rolling uphill: in vivo reacquisition of pluripotency during cranial neural crest differentiation
Conrad Waddington famously used his epigenetic landscape to describe the paths a cell might take during developmental differentiation. In this analogy, the undifferentiated stem cell begins at the highest elevation and proceeds to tumble downward towards its final resting place, representing termina...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137701/ https://www.ncbi.nlm.nih.gov/pubmed/34017055 http://dx.doi.org/10.1038/s42003-021-02154-6 |