Lysosome-Dependent LXR and PPARδ Activation Upon Efferocytosis in Human Macrophages

Efferocytosis is critical for tissue homeostasis, as its deregulation is associated with several autoimmune pathologies. While engulfing apoptotic cells, phagocytes activate transcription factors, such as peroxisome proliferator-activated receptors (PPAR) or liver X receptors (LXR) that orchestrate...

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Detalles Bibliográficos
Autores principales: Mota, Ana Carolina, Dominguez, Monica, Weigert, Andreas, Snodgrass, Ryan G., Namgaladze, Dmitry, Brüne, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137840/
https://www.ncbi.nlm.nih.gov/pubmed/34025647
http://dx.doi.org/10.3389/fimmu.2021.637778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137840/
https://www.ncbi.nlm.nih.gov/pubmed/34025647
http://dx.doi.org/10.3389/fimmu.2021.637778

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