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Diversity-oriented functionalization of 2-pyridones and uracils

Heterocycles 2-pyridone and uracil are privileged pharmacophores. Diversity-oriented synthesis of their derivatives is in urgent need in medicinal chemistry. Herein, we report a palladium/norbornene cooperative catalysis enabled dual-functionalization of iodinated 2-pyridones and uracils. The succes...

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Detalles Bibliográficos
Autores principales: Shang, Yong, Wu, Chenggui, Gao, Qianwen, Liu, Chang, Li, Lisha, Zhang, Xinping, Cheng, Hong-Gang, Liu, Shanshan, Zhou, Qianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137914/
https://www.ncbi.nlm.nih.gov/pubmed/34016986
http://dx.doi.org/10.1038/s41467-021-23058-3