The impact of chromosomal fusions on 3D genome folding and recombination in the germ line

The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear. Here, we take advantage of chromosome conformation capture in combination with single-nucleotide polymorphism (SNP) genotyping a...

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Detalles Bibliográficos
Autores principales: Vara, Covadonga, Paytuví-Gallart, Andreu, Cuartero, Yasmina, Álvarez-González, Lucía, Marín-Gual, Laia, Garcia, Francisca, Florit-Sabater, Beatriu, Capilla, Laia, Sanchéz-Guillén, Rosa Ana, Sarrate, Zaida, Aiese Cigliano, Riccardo, Sanseverino, Walter, Searle, Jeremy B., Ventura, Jacint, Marti-Renom, Marc A., Le Dily, François, Ruiz-Herrera, Aurora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137915/
https://www.ncbi.nlm.nih.gov/pubmed/34016985
http://dx.doi.org/10.1038/s41467-021-23270-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137915/
https://www.ncbi.nlm.nih.gov/pubmed/34016985
http://dx.doi.org/10.1038/s41467-021-23270-1

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