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The impact of chromosomal fusions on 3D genome folding and recombination in the germ line
The spatial folding of chromosomes inside the nucleus has regulatory effects on gene expression, yet the impact of genome reshuffling on this organization remains unclear. Here, we take advantage of chromosome conformation capture in combination with single-nucleotide polymorphism (SNP) genotyping a...
Autores principales: | Vara, Covadonga, Paytuví-Gallart, Andreu, Cuartero, Yasmina, Álvarez-González, Lucía, Marín-Gual, Laia, Garcia, Francisca, Florit-Sabater, Beatriu, Capilla, Laia, Sanchéz-Guillén, Rosa Ana, Sarrate, Zaida, Aiese Cigliano, Riccardo, Sanseverino, Walter, Searle, Jeremy B., Ventura, Jacint, Marti-Renom, Marc A., Le Dily, François, Ruiz-Herrera, Aurora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137915/ https://www.ncbi.nlm.nih.gov/pubmed/34016985 http://dx.doi.org/10.1038/s41467-021-23270-1 |
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