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Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A

The epithelial–mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating the identification of molecules that induce cell death specifically in stem-like cells with EMT properties. Herein, we demonstrate that brea...

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Detalles Bibliográficos
Autores principales: Reisenauer, Keighley N., Tao, Yongfeng, Das, Provas, Song, Shuxuan, Svatek, Haleigh, Patel, Saawan D., Mikhail, Sheridan, Ingros, Alec, Sheesley, Peter, Masi, Marco, Boari, Angela, Evidente, Antonio, Kornienko, Alexander, Romo, Daniel, Taube, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137940/
https://www.ncbi.nlm.nih.gov/pubmed/34017048
http://dx.doi.org/10.1038/s41598-021-89923-9