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Exosomal microRNA-503-3p derived from macrophages represses glycolysis and promotes mitochondrial oxidative phosphorylation in breast cancer cells by elevating DACT2

MicroRNAs (miRNAs) are emerging drivers in tumor progression, while the role of miR-503-3p in breast cancer (BC) remains largely unknown. We aimed to explore the impact of macrophage-derived exosomal miR-503-3p in the development of BC by regulating disheveled-associated binding antagonist of beta-c...

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Detalles Bibliográficos
Autores principales: Huang, Shulin, Fan, Peizhi, Zhang, Chaojie, Xie, Jing, Gu, Xiaowen, Lei, Shanshan, Chen, Zihua, Huang, Zhongcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137952/
https://www.ncbi.nlm.nih.gov/pubmed/34016964
http://dx.doi.org/10.1038/s41420-021-00492-2