Cargando…

TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel

Animal cells can regulate their volume after swelling by the regulatory volume decrease (RVD) mechanism. In epithelial cells, RVD is attained through KCl release mediated via volume-sensitive outwardly rectifying Cl(−) channels (VSOR) and Ca(2+)-activated K(+) channels. Swelling-induced activation o...

Descripción completa

Detalles Bibliográficos
Autores principales: Numata, Tomohiro, Sato-Numata, Kaori, Hermosura, Meredith C., Mori, Yasuo, Okada, Yasunobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137958/
https://www.ncbi.nlm.nih.gov/pubmed/34017036
http://dx.doi.org/10.1038/s42003-021-02127-9