TSP50 promotes the Warburg effect and hepatocyte proliferation via regulating PKM2 acetylation

Metabolic reprogramming is a hallmark of malignancy. Testes-specific protease 50 (TSP50), a newly identified oncogene, has been shown to play an important role in tumorigenesis. However, its role in tumor cell metabolism remains unclear. To investigate this issue, LC–MS/MS was employed to identify T...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Feng, Zhang, Xiaojun, Wang, Shuyue, Zheng, Lihua, Sun, Ying, Wang, Guannan, Song, Zhenbo, Bao, Yongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138007/
https://www.ncbi.nlm.nih.gov/pubmed/34016961
http://dx.doi.org/10.1038/s41419-021-03782-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138007/
https://www.ncbi.nlm.nih.gov/pubmed/34016961
http://dx.doi.org/10.1038/s41419-021-03782-w

Ejemplares similares