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TSP50 promotes the Warburg effect and hepatocyte proliferation via regulating PKM2 acetylation
Metabolic reprogramming is a hallmark of malignancy. Testes-specific protease 50 (TSP50), a newly identified oncogene, has been shown to play an important role in tumorigenesis. However, its role in tumor cell metabolism remains unclear. To investigate this issue, LC–MS/MS was employed to identify T...
Autores principales: | Gao, Feng, Zhang, Xiaojun, Wang, Shuyue, Zheng, Lihua, Sun, Ying, Wang, Guannan, Song, Zhenbo, Bao, Yongli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138007/ https://www.ncbi.nlm.nih.gov/pubmed/34016961 http://dx.doi.org/10.1038/s41419-021-03782-w |
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