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Attenuated dengue viruses are genetically more diverse than their respective wild-type parents
Dengue poses a significant burden of individual health, health systems and the economy in dengue endemic regions. As such, dengue vaccine development has been an active area of research. Previous studies selected attenuated vaccine candidates based on plaque size. However, these candidates led to mi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138019/ https://www.ncbi.nlm.nih.gov/pubmed/34017007 http://dx.doi.org/10.1038/s41541-021-00340-5 |