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An emm-type specific qPCR to track bacterial load during experimental human Streptococcus pyogenes pharyngitis

BACKGROUND: Streptococcus pyogenes causes a profound global burden of morbidity and mortality across its diverse clinical spectrum. To support a new controlled human infection (challenge) model seeking to accelerate S. pyogenes vaccine development, we aimed to develop an accurate and reliable molecu...

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Detalles Bibliográficos
Autores principales: Fabri, Loraine V., Azzopardi, Kristy I., Osowicki, Joshua, Frost, Hannah R., Smeesters, Pierre R., Steer, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138111/
https://www.ncbi.nlm.nih.gov/pubmed/34020607
http://dx.doi.org/10.1186/s12879-021-06173-w