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Bcl-xL mutant promotes cartilage differentiation of BMSCs by upregulating TGF-β/BMP expression levels

Bcl-xL is a transmembrane molecule in the mitochondria, with apoptosis-related and pro-metabolic functions, that also plays a role in chondrogenesis and differentiation. A Bcl-xL mutant, in which the GRI sequence is replaced by ELN, has no anti-apoptotic effect, while other biological functions of t...

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Detalles Bibliográficos
Autores principales: Xiao, Kai, Yang, Lin, Xie, Wei, Gao, Xinfeng, Huang, Ruokun, Xie, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138271/
https://www.ncbi.nlm.nih.gov/pubmed/34055053
http://dx.doi.org/10.3892/etm.2021.10168