Cargando…
Intracellular versus extracellular inhibition of calpain I causes differential effects on pain in a rat model of joint inflammation
Calpain I is a calcium-dependent cysteine protease which has dual effects on tissue inflammation depending on its cellular location. Intracellularly, calpain I has pro-inflammatory properties but becomes anti-inflammatory when exteriorised into the extracellular space. In this study, the effect of c...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138287/ https://www.ncbi.nlm.nih.gov/pubmed/34006144 http://dx.doi.org/10.1177/17448069211016141 |