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Attenuation of High Glucose-Induced Damage in RPE Cells through p38 MAPK Signaling Pathway Inhibition

This study aimed to investigate the high glucose damage on human retinal pigment epithelial (RPE) cells, the role of p38 MAPK signaling pathway and how dimethyl fumarate can regulate that. We carried out in vitro studies on ARPE-19 cells exposed to physiological and high glucose (HG) conditions, to...

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Detalles Bibliográficos
Autores principales: Maugeri, Grazia, Bucolo, Claudio, Drago, Filippo, Rossi, Settimio, Di Rosa, Michelino, Imbesi, Rosa, D’Agata, Velia, Giunta, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138305/
https://www.ncbi.nlm.nih.gov/pubmed/34025440
http://dx.doi.org/10.3389/fphar.2021.684680