Integrated Isogenic Human Induced Pluripotent Stem Cell–Based Liver and Heart Microphysiological Systems Predict Unsafe Drug–Drug Interaction

Three-dimensional (3D) microphysiological systems (MPSs) mimicking human organ function in vitro are an emerging alternative to conventional monolayer cell culture and animal models for drug development. Human induced pluripotent stem cells (hiPSCs) have the potential to capture the diversity of hum...

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Detalles Bibliográficos
Autores principales: Lee-Montiel, Felipe T., Laemmle, Alexander, Charwat, Verena, Dumont, Laure, Lee, Caleb S., Huebsch, Nathaniel, Okochi, Hideaki, Hancock, Matthew J., Siemons, Brian, Boggess, Steven C., Goswami, Ishan, Miller, Evan W., Willenbring, Holger, Healy, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138446/
https://www.ncbi.nlm.nih.gov/pubmed/34025426
http://dx.doi.org/10.3389/fphar.2021.667010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138446/
https://www.ncbi.nlm.nih.gov/pubmed/34025426
http://dx.doi.org/10.3389/fphar.2021.667010

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