XIAP Knockdown in Alcohol-Associated Liver Disease Models Exhibits Divergent in vitro and in vivo Phenotypes Owing to a Potential Zonal Inhibitory Role of SMAC

Alcohol-associated liver disease (ALD) has been recognized as the most common cause of advanced liver disease worldwide, though mechanisms of pathogenesis remain incompletely understood. The X-linked inhibitor of apoptosis (XIAP) protein was originally described as an anti-apoptotic protein that dir...

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Detalles Bibliográficos
Autores principales: He, Li, Sehrawat, Tejasav S., Verma, Vikas K., Navarro-Corcuera, Amaia, Sidhu, Guneet, Mauer, Amy, Luo, Xin, Katsumi, Tomohiro, Chen, Jingbiao, Shah, Soni, Arab, Juan Pablo, Cao, Sheng, Kashkar, Hamid, Gores, Gregory J., Malhi, Harmeet, Shah, Vijay H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138467/
https://www.ncbi.nlm.nih.gov/pubmed/34025452
http://dx.doi.org/10.3389/fphys.2021.664222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138467/
https://www.ncbi.nlm.nih.gov/pubmed/34025452
http://dx.doi.org/10.3389/fphys.2021.664222

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