CYP2D6 in the Brain: Potential Impact on Adverse Drug Reactions in the Central Nervous System—Results From the ADRED Study

Cytochrome P450 (CYP) 2D6 is a polymorphic enzyme expressed in the central nervous system (CNS), important in drug metabolism and with a potentially constitutive role in CNS function such as vigilance. This study aimed to analyze variability in CYP2D6 activity linked to vigilance-related adverse dru...

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Detalles Bibliográficos
Autores principales: Just, Katja S., Dormann, Harald, Freitag, Mathias, Schurig, Marlen, Böhme, Miriam, Steffens, Michael, Scholl, Catharina, Seufferlein, Thomas, Graeff, Ingo, Schwab, Matthias, Stingl, Julia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138470/
https://www.ncbi.nlm.nih.gov/pubmed/34025403
http://dx.doi.org/10.3389/fphar.2021.624104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138470/
https://www.ncbi.nlm.nih.gov/pubmed/34025403
http://dx.doi.org/10.3389/fphar.2021.624104

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