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Downregulated MicroRNA-327 Attenuates Oxidative Stress–Mediated Myocardial Ischemia Reperfusion Injury Through Regulating the FGF10/Akt/Nrf2 Signaling Pathway

Although miR-327 had a protective effect on cardiomyocytes as described previously, the potential mechanism still needs further exploration. The aim of this study was to investigate the role and mechanism of miR-327 on oxidative stress in myocardial ischemia/reperfusion injury (MI/RI) process. Oxida...

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Detalles Bibliográficos
Autores principales: Zheng, Tao, Yang, Jun, Zhang, Jing, Yang, Chaojun, Fan, Zhixing, Li, Qi, Zhai, Yuhong, Liu, Haiyin, Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138475/
https://www.ncbi.nlm.nih.gov/pubmed/34025428
http://dx.doi.org/10.3389/fphar.2021.669146