Safety, tolerability, and immune-biomarker profiling for year-long sargramostim treatment of Parkinson's disease

BACKGROUND: Neuroinflammation plays a pathogenic role in Parkinson's disease (PD). Immunotherapies that restore brain homeostasis can mitigate neurodegeneration by transforming T cell phenotypes. Sargramostim has gained considerable attention as an immune transformer through laboratory bench to...

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Detalles Bibliográficos
Autores principales: Olson, Katherine E., Namminga, Krista L., Lu, Yaman, Schwab, Aaron D., Thurston, Mackenzie J., Abdelmoaty, Mai M., Kumar, Vikas, Wojtkiewicz, Melinda, Obaro, Helen, Santamaria, Pamela, Mosley, R. Lee, Gendelman, Howard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138485/
https://www.ncbi.nlm.nih.gov/pubmed/34000620
http://dx.doi.org/10.1016/j.ebiom.2021.103380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138485/
https://www.ncbi.nlm.nih.gov/pubmed/34000620
http://dx.doi.org/10.1016/j.ebiom.2021.103380

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