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Selective inhibition of JNK mitochondrial location is protective against seawater inhalation-induced ALI/ARDS
Localization of phosphorylated (p)-JNK to the mitochondria can lead to functional mitochondrial disorder, resulting in a decrease in energy supply and membrane potential, as well as an increase in reactive oxygen species production and apoptosis. JNK is involved in the occurrence of acute lung injur...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138518/ https://www.ncbi.nlm.nih.gov/pubmed/34013361 http://dx.doi.org/10.3892/mmr.2021.12154 |