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Selective inhibition of JNK mitochondrial location is protective against seawater inhalation-induced ALI/ARDS

Localization of phosphorylated (p)-JNK to the mitochondria can lead to functional mitochondrial disorder, resulting in a decrease in energy supply and membrane potential, as well as an increase in reactive oxygen species production and apoptosis. JNK is involved in the occurrence of acute lung injur...

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Detalles Bibliográficos
Autores principales: Bo, Liyan, Li, Yanyan, Liu, Wei, Jin, Faguang, Li, Congcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138518/
https://www.ncbi.nlm.nih.gov/pubmed/34013361
http://dx.doi.org/10.3892/mmr.2021.12154