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Selective inhibition of JNK mitochondrial location is protective against seawater inhalation-induced ALI/ARDS
Localization of phosphorylated (p)-JNK to the mitochondria can lead to functional mitochondrial disorder, resulting in a decrease in energy supply and membrane potential, as well as an increase in reactive oxygen species production and apoptosis. JNK is involved in the occurrence of acute lung injur...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138518/ https://www.ncbi.nlm.nih.gov/pubmed/34013361 http://dx.doi.org/10.3892/mmr.2021.12154 |