Crystal structures of inhibitor complexes of M‐PMV protease with visible flap loops

Mason‐Pfizer monkey virus protease (PR) was crystallized in complex with two pepstatin‐based inhibitors in P1 space group. In both crystal structures, the extended flap loops that lock the inhibitor/substrate over the active site, are visible in the electron density either completely or with only sm...

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Detalles Bibliográficos
Autores principales: Wosicki, Stanislaw, Kazmierczyk, Maciej, Gilski, Miroslaw, Zabranska, Helena, Pichova, Iva, Jaskolski, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Protein Structure Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138519/
https://www.ncbi.nlm.nih.gov/pubmed/33786913
http://dx.doi.org/10.1002/pro.4072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138519/
https://www.ncbi.nlm.nih.gov/pubmed/33786913
http://dx.doi.org/10.1002/pro.4072

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