Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of β-catenin and regulation of its stability

BACKGROUND: Oxidative stress plays critical pathophysiological roles in vascular remodeling-related cardiovascular diseases, including hypertension, atherosclerosis, and restenosis. Previous studies demonstrate that SENP3, a redox-sensitive SUMO2/3-specific protease, is strongly implicated in cancer...

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Detalles Bibliográficos
Autores principales: Cai, Zhaohua, Wang, Zi, Yuan, Ruosen, Cui, Mingli, Lao, Yimin, Wang, Ying, Nie, Peng, Shen, Linghong, Yi, Jing, He, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138600/
https://www.ncbi.nlm.nih.gov/pubmed/34000626
http://dx.doi.org/10.1016/j.ebiom.2021.103386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138600/
https://www.ncbi.nlm.nih.gov/pubmed/34000626
http://dx.doi.org/10.1016/j.ebiom.2021.103386

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