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Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of β-catenin and regulation of its stability

BACKGROUND: Oxidative stress plays critical pathophysiological roles in vascular remodeling-related cardiovascular diseases, including hypertension, atherosclerosis, and restenosis. Previous studies demonstrate that SENP3, a redox-sensitive SUMO2/3-specific protease, is strongly implicated in cancer...

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Detalles Bibliográficos
Autores principales:	Cai, Zhaohua, Wang, Zi, Yuan, Ruosen, Cui, Mingli, Lao, Yimin, Wang, Ying, Nie, Peng, Shen, Linghong, Yi, Jing, He, Ben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138600/ https://www.ncbi.nlm.nih.gov/pubmed/34000626 http://dx.doi.org/10.1016/j.ebiom.2021.103386

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